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Esketamine reduces the fluctuations in vital signs during induced abortion operation

Esketamine reduces the fluctuations in vital signs during induced abortion operation: a single center, prospective, double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300079120
Enrollment
Unknown
Registered
2023-12-26
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

induced abortion operation

Interventions

esketamine anesthesia group:The anesthesia induction plan is propofol 2.0mg/kg+esketamine 0.1mg/kg iv
sufentanil anesthesia group:The anesthesia induction plan is propofol 2.0mg/kg+sufentanil 0.1ug/kg iv

Sponsors

Weihai Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: ?Female of childbearing age, intend to painless induced abortion; ?No serious comorbidities, such as unstable angina and poor control of severe hypertension; ?Able to cooperate in communication and complete follow-up indicators; ?Sign an informed consenf form;

Exclusion criteria

Exclusion criteria: ?Previous history of major surgeries, such as heart surgery, craniotomy, etc; ?There are contraindications to the use of eskatamine, such as severe hypertension and poorly controlled asthma; ?Allergy to research medication; ?Patients with mental illness cannot cooperate with follow-up;

Design outcomes

Primary

MeasureTime frame
Patient's systolic blood pressure, diastolic blood pressure, mean blood pressure, herat rate and breathing;

Secondary

MeasureTime frame
Whether the patient have body movement during the operation and whether additional propofol was needed.;Intraoperative hypoxemia(SpO2<90% or artificial ventilation support is required);The patient experiences nausea, vomiting and dizziness;Patient pain after resuscitation(NRS scoring system);RAAS score after resuscitation(evaluation for sedation-agitation with a score ranging from -3 to + 3,0 being fully awake);

Countries

China

Contacts

Public ContactGuan Yingchao

Weihai Municipal Hospital

Gvwalgiya1993@foxmail.com+86 156 5013 8341

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026