Ascites in hepatitis B virus-related cirrhosis
Conditions
Interventions
Test group:Basic internal medicine treatment plus Strengthening Spleen and Tonifying Kidney Granules
Control group:Basic internal medicine treatment plus placebo
Sponsors
The First Affiliated Hospital of Henan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 65 years. (2) Meet the diagnostic criteria for ascites in hepatitis B-related cirrhosis and spleen and kidney deficiency. (3) Disappearance or maximum depth of ascites less than 3 cm on ultrasound after comprehensive medical treatment. (4) Voluntarily participate in the research, sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Those who are participating in other clinical studies. (2) Liver failure. (3) Combined with complications such as hepatic encephalopathy, hepatorenal syndrome, upper gastrointestinal bleeding, and spontaneous peritonitis. (4) Primary liver cancer, or tumours in other parts of the body. (5) Allergy to a certain component of this formula. (6) Severe cardiac, renal, pulmonary, cerebral, diabetic and other fundamental diseases, ascites due to constrictive pericarditis, tuberculous peritonitis, and tumours. (7) Pregnant or lactating women. (8) Patients after transjugular intrahetic portosystemicshunt (Tips). (9) Other conditions that the investigator considers inappropriate for enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of ascites; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of days sustained without recurrence of ascites;Maximum depth of ascites in the lower abdomen on ultrasound;serum albumin;serum pre-albumin;serum cholinesterase;symptoms; | — |
Countries
China
Contacts
Public ContactSuping Ma
The First Affiliated Hospital of Henan University of Chinese Medicine
Outcome results
None listed