Jaw defect caused by trauma or tumor
Conditions
Interventions
Position frame group:A special position frame was used during the preparation of the vascularized fibula flap
No position frame group:No special position frame was used in the preparation of the vascularized fibula flap
Sponsors
West china hospital of stomatology, Sichuan university
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age =18 years old and =75 years old, gender is not limited; (2) Jaw defects caused by various factors were confirmed by imaging and received surgical treatment with vascularized fibula flap transplantation; (3) Full organ and bone marrow function (4) The subjects voluntarily join the study, sign the informed consent, and comply with the visit and related procedures stipulated in the program.
Exclusion criteria
Exclusion criteria: (1) any active autoimmune disease or history of autoimmune disease, (2) Allergic disease, severe drug allergy, known to be allergic to macromolecular protein preparations; (3) Patients with serious medical diseases; (4) have an active infection, or an unexplained fever during screening, or use of systemic antibiotics within 1 week before signing informed consent; (5) The subject has active hepatitis B or C, or a known history of testing positive for human immunodeficiency virus (HIV) or a known history of acquired immunodeficiency syndrome (AIDS); (6) A prior history of a definite neurological or mental disorder, such as epilepsy or dementia; (7) have a clear history of drug abuse or a history of alcohol abuse within 3 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ankle flexion;Knee flexion;Hip flexion; | — |
Secondary
| Measure | Time frame |
|---|---|
| patients' subjective experiences evaluation; | — |
Countries
China
Contacts
Public ContactChen Jing
West china hospital of stomatology, Sichuan university
Outcome results
None listed