Skip to content

Effectiveness and predictive factors of ustekinumab intensi?cation in Crohn's disease——a monocentric real-world study

Effectiveness and predictive factors of ustekinumab intensi?cation in Crohn's disease——a monocentric real-world study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300079089
Enrollment
Unknown
Registered
2023-12-25
Start date
2023-12-25
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease

Interventions

Patients treated with Ustekinumab (UST) were followed up for at least one year:NA

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 100 Years

Inclusion criteria

Inclusion criteria: ?CD patients hospitalized in the Gastroenterology Department of Wuhan Tongji Hospital from September 2020 to September 2023, all patients comply with the "Consensus on the Diagnosis and Treatment of Inflammatory Bowel Disease" formulated by the Gastroenterology Branch of the Chinese Medical Association (Beijing Conference) in 2018 Opinion>Diagnostic Criteria for CD. ?Follow-up time exceeds 12 months. ?Complete UST induction treatment and maintain treatment for 12 months. ?Complete clinical information and follow-up data

Exclusion criteria

Exclusion criteria: ?Patients with lack of baseline data. ?Does not meet the diagnostic criteria of the consensus opinion on the diagnosis and treatment of inflammatory bowel disease CD developed by the Digestive Disease Branch of the Chinese Medical Association (Beijing Conference) in 2018. ?Routine infection-related examinations to rule out infectious enteritis such as intestinal tuberculosis. ?Patients who were lost to follow-up or whose data are incomplete.

Design outcomes

Primary

MeasureTime frame
clinical remission ;endoscopic remission;

Secondary

MeasureTime frame
Clinical response;endoscopic response;imaging response and remission rate;Changes in serum and nutritional indicators;

Countries

China

Contacts

Public ContactQin Yu

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology

yuqin@tjh.tjmu.edu.cn+86 130 0714 2803

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026