gastrointestinal disease
Conditions
Interventions
eskatamine group:Esketamine 0.5mg/kg was added for induction
control group :regular anesthesia induction
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients undergoing general anesthesia surgery, and the operation time is <3h; (2) Age: 65-80 years old, gender is not limited; (3) ASA: I-II level; (4) 18kg/m2 < BMI < 30kg/m2; (5) Clearly understand and voluntarily participate in the study, and signed by their own or family members informed consent.
Exclusion criteria
Exclusion criteria: (1) severe respiratory, circulatory and nervous system diseases; (2) Mental illness diagnosed before surgery; (3) dysfunction of vital organs such as liver and kidney; (4) Obesity (BMI > 30kg/m2); (5) Difficulty in intubation or mask ventilation occurred during the preoperatively anticipated induction process; (6) Allergies or contraindications of drugs and solvents involved in this study; (7) long-term use of sedatives, analgesics and large amounts of alcohol and drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRP;PCT;NE;Cognitive Function; | — |
Countries
China
Contacts
Public ContactLiu Qilin
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed