head and neck tumor
Conditions
Interventions
Case series:None
Sponsors
Zhongshan Hospital Affiliated to Dalian University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Sign the informed consent voluntarily. Age=18, gender is not limited. ECOG score: 0-4 points. The subjects have good compliance, can comply with the procedures related to learning, and are able and willing to complete the questionnaire surveys related to their environmental/occupational exposure and smoking/drinking history. Any patient with head and neck cancer of any subtype and stage. Primary or metastatic lesions can obtain surgical tissue or sufficient biopsy tissue, which can provide tumor tissue samples for culture. Life expectancy is not less than 12 weeks. The main organs function normally, and the heart, liver, kidney, and bone marrow hematopoietic functions are good.
Exclusion criteria
Exclusion criteria: 1) Those under 18 years old. 2) History of severe neurological or psychiatric disorders, including seizures or dementia, physical or mental incapacity or inability to sign informed consent, and inability to give informed consent (language, intelligence, etc.). 3)Refusal to participate. 4)It is impossible to obtain samples such as biopsy and/or surgery, pleural effusion, ascites, pericardial effusion, and cerebrospinal fluid. 5)There is not enough head and neck tumor tissue for histological analysis or the remaining head and neck tumor tissue is not sufficient for routine pathological analysis. 6)Those who are allergic to anti-tumor drugs or have surgical contraindications and cannot receive any anti-tumor treatment. 7)Any other history of clinically active malignant tumor within the first 5 years of enrollment 8)According to the attending physician's judgment, the patient will not be able to meet the requirements of the study. 9)Serious liver disease, cardiovascular disease, kidney disease, respiratory system disease, blood system disease or out of control diabetes. 10)HIV patients. 11)Pregnant and lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Organoid characteristics and drug sensitivity; | — |
Countries
China
Contacts
Public ContactRuoyu Wang
Zhongshan Hospital Affiliated to Dalian University
Outcome results
None listed