Anxiety and depression
Conditions
Interventions
Observation group (Esketamine group) :Esketamine used
Control group (non Esketamine group):Non esketamine
Sponsors
The Second Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: infertile patients who underwent daytime combined exploration of the uterus and abdomen and microscopic sperm extraction for the first time, aged 25-45 years old, ASA I or II, BMI 18-30kg/m ²
Exclusion criteria
Exclusion criteria: Refusing to participate in this study; History of chronic pain; Take analgesics 24 hours before surgery; History of mental and psychological disorders; History of adverse reactions related to the treatment of Esketamine; Refusing to score on the Hospital Anxiety and Depression Scale (HADS) in a comprehensive hospital; Surgical time>4 hours; Bleeding during surgery>500 ml; Laparoscopic conversion to open surgery during surgery; (5) Those who fail to complete the HADS score or pain score.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Anxiety and Depression Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative sleep quality;Postoperative NRS score; | — |
Countries
China
Contacts
Public ContactWang Shizhao
The Second Hospital of Hebei Medical University
Outcome results
None listed