hypertensive intracerebral hemorrhage
Conditions
Interventions
Treat group:PRP3ml was slowly injected into the hematoma
Control group:5ml of sterile normal saline was slowly injected into the hematoma
Sponsors
Department of Neurosurgery ,General Hospital of Southern Theater Command, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age =18 years old, =70 years old; 2. No aspirin, hydroclopidogrel, indobuprofen and other antiplatelet drugs were taken within 1 week before the onset of ICH; No history of using rivaroxaban, dabigatran, heparin and other anticoagulant drugs; 3. No history of infection; 4. Routine blood test showed no abnormality in platelet and hemoglobin; 5. The patient was diagnosed with hypertensive cerebral hemorrhage, and the volume of intracranial hematoma shown by CT was less than 60ml, and there was no clinical tendency of cerebral hernia.
Exclusion criteria
Exclusion criteria: 1. Age 70 years old; 2. Antiplatelet drugs such as aspirin, hydroclopidogrel and indolbuprofen, or anticoagulant drugs such as rivaroxaban, dabigatron and heparin were taken within 1 week before the onset of ICH; 3. suffer from infectious diseases; 4. Patients with non-hypertensive cerebral hemorrhage; 5.CT confirmed that the intracranial hematoma was larger than 60ml or clinically indicated that the patient had a tendency of cerebral hernia; 6. Patients with malignant tumor, intracranial infection, severe cardiovascular disease, moderate to severe hepatorenal insufficiency or the surgeon thought it was not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glasgow Outcome Scale ;muscle strength;Montreal Cognitive Assessment;Mini-Mental State Examination;HamiltonDepressionScale;White matter bundle density; | — |
Countries
China
Contacts
Public ContactHongmin Bai
Department of Neurosurgery ,General Hospital of Southern Theater Command, PLA
Outcome results
None listed