ICU-acquired weakness
Conditions
Interventions
Intervention group:nutritional enhancement and blood glucose control
Control group:conventional clinical management measures
Sponsors
THE SECOND AFFILIATED HOSPITAL ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age =18 years; Recipients of lung transplantation; Able to understand the purpose and potential risks of the study and sign an informed consent form
Exclusion criteria
Exclusion criteria: ? Rapidly changing brain diseases (such as extensive stroke, intracranial hemorrhage, status epilepticus), traumatic brain injury, cognitive impairment, increased intracranial pressure. ? Requires bed rest/both lower limbs cannot bear weight, fractures, disabilities. ? Presence of spinal cord injury or other neuromuscular diseases (resulting in permanent or long-term muscle weakness), previous history of abnormal muscle strength (muscle strength less than grade 5 in any limb). ? History of cardiac arrest. ? Non-first lung transplantation, or other transplants (including hematopoietic stem cell transplantation) in the past. ? The subject has participated in another conflicting clinical study. ? Pregnancy status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRC score; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28 days without ventilator;Mechanical ventilation time;ICU stay;In-hospital mortality rate;No assisted walking distance at ICU discharge;the Barthelindex of ADL;Calories and protein delivered;Proportion of nutritional deficiencies;Incidence of hypoglycemia;Proportion of enteral nutrition intolerance; | — |
Countries
China
Contacts
Public ContactHuang Man
THE SECOND AFFILIATED HOSPITAL ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE
Outcome results
None listed