Acute Ischemic Stroke
Conditions
Interventions
Treatment group:Emerge angioplasty/or stenting combined with standard medical treatment
Sponsors
Jinan University First Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Age = 18 years, gender not specified. (2) Onset to puncture time within 24 hours. This includes Wake-up stroke or patients without witnesses to the stroke; the time of symptom onset is defined as the "Last Known Well" (LKW) time. If onset to puncture is 1 but unrelated to neurological diseases (such as blindness, amputation, etc.). (5) Patient or their legal representative signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Severe organ (heart, lung, kidney, liver) failure. (2) Platelet count less than 40×10^9/L. (3) Currently using anticoagulants with a severe bleeding tendency (international normalized ratio >3) or active bleeding. (4) Severe uncontrolled hypertension. (5) Imaging shows intracranial hemorrhage, severe mass effect, tumors requiring surgical treatment, extracranial segment occlusion of the cervical internal carotid artery, simultaneous occlusion of multiple major arteries, moyamoya disease occlusion, or tandem occlusion. (6) Non-atherosclerotic stenosis, such as arteritis, vascular spasm, dissection, or NIHSS score =25 upon admission. (7) Pregnant women. (8) Participants involved in other studies conflicting with the current study. (9) Other situations where researchers believe it is inappropriate for individuals to participate in the study or may pose significant risks to patients (such as cognitive impairment preventing understanding and/or compliance with the study procedures and/or follow-up).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of ischemic stroke in the responsible vessel watershed within 90 ± 7 days after randomization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of responsible vessel re-occlusion within 7 ± 1 days after randomization;mRS 0-2 within 90 ± 7 days after random fraction; | — |
Countries
China
Contacts
Public ContactHuang Li'an
Jinan University First Affiliated Hospital
Outcome results
None listed