Postoperative pulmonary complications
Conditions
Interventions
Group C:Lung protective ventilation group with constant PEEP
Group D:Individualized PEEP group guided by driving pressure
Sponsors
Beijing Tongren Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients who plan to undergo laparoscopic surgery, the estimated duration greater than 2 hours 2.Age>18 years old 3.The body mass index<30kg/m2 4.American Society of Anesthesiologists (ASA) class I to III 5.ARISCAT score = 26 points
Exclusion criteria
Exclusion criteria: 1.Patients with severe acute and chronic lung diseases, including respiratory failure, pneumothorax, pulmonary bullae, chronic obstructive pulmonary disease, pulmonary infection, bronchiectasis, and poorly controlled asthma 2.Patients with severe cardiovascular complications and NYHA grade III-IV 3.Patients who have undergone thoracic surgery or have a history of mechanical ventilation within 4 weeks 4.Patients with other contraindications for PEEP, including high intracranial pressure, bronchopleural fistula and hypovolemic shock
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung ultrasound score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung ultrasound score;Postoperative pulmonary complications;Intraoperative respiratory mechanics;Blood gas analysis;inflammatory factors;Intraoperative hemodynamics;Postoperative NRS score;Postoperative hospital stay;Long term prognostic indicators; | — |
Countries
China
Contacts
Public ContactGuyan Wang
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed