painless gastroscopy
Conditions
Interventions
Normal group:The biased coin design (BCD) were used,the initial dose of ciprofol was set to 0.2 mg/kg and the dose gradient was 0.04 mg/kg. When movement, choking, swallowing and other reactions, seda
Overweight group:The biased coin design (BCD) were used,the initial dose of ciprofol was set to 0.2 mg/kg and the dose gradient was 0.04 mg/kg. When movement, choking, swallowing and other reactions,
Obesity group:The biased coin design (BCD) were used,the initial dose of ciprofol was set to 0.2 mg/kg and the dose gradient was 0.04 mg/kg. When movement, choking, swallowing and other reactions, sed
Sponsors
Baoding NO.1 Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients to undergo elective painless gastroscopy; 2, Age 18-65 years; 3, ASA grade ? or ?; 4, Mouth opening = 2.5 cm; 5, Normal head and neck mobility; 6, Mallampati grade? or ?; 7. Patients have fully understood the nature of the study and voluntarily participate in the trial and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. History of allergy to test drugs; 2. History of neurological diseases; 3. High risk of inhalation; 4. Expected airway difficulty; 5. Long term use of sedatives; 6. Acute upper gastrointestinal bleeding; 7. Investigators considered any conditions inappropriate to be selected for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 95% effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects such as bradycardia, hypotension, hypoxia, choking, body movement, and swallowing during the induction period;SpO2, HR and MAP were recorded before anesthesia (T0), 1min after injection (T1) and gastroscopy (T2); | — |
Countries
China
Contacts
Public ContactChunguang Wang
Baoding NO.1 Central Hospital
Outcome results
None listed