Functional dyspepsia
Conditions
Interventions
Experimental group:Shisanwei Hezhong Pill and Mosapride Citrate Simulated Capsule
Control group 1:Shisanwei Hezhong Pill simulation agent and Mosapride Citrate Capsules
Control group 2 :Shisanwei Hezhong Pill and Mosapride Citrate Capsules
Sponsors
The second affiliated Hospital of Anhui University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ( 1 ) According to the diagnostic criteria of Rome IV functional dyspepsia and liver-stomach disharmony type of traditional Chinese medicine ; ( 2 ) 18 years old = age = 65 years old, regardless of gender ; ( 3 ) Subjects signed informed consent voluntarily with their informed consent ; ( 4 ) Have a certain reading ability. ( Note : Patients who meet the above four criteria at the same time can be included in this study. )
Exclusion criteria
Exclusion criteria: ( 1 ) Complicated with gastric and twelve intestinal ulcers, mucosal erosion and bleeding under gastroscope, pathological examination showed gastric mucosal atrophy, intestinal metaplasia or dysplasia, or systemic diseases affecting gastrointestinal motility ( such as diabetes, chronic renal insufficiency, connective tissue disease, mental and neurological diseases, etc. ) ; ( 2 ) Have taken or are taking drugs or antibiotics that affect gastrointestinal motility or gastric acid secretion within 2 weeks ; ( 3 ) Patients with severe brain, heart, liver, kidney, lung, hematopoietic system, endocrine system and autoimmune diseases ; ( 4 ) malignant tumors or other serious consumptive diseases, infectious diseases, hemorrhagic diseases, etc. ; ( 5 ) those with severe mental and psychological disorders ( HAMA = 21 points with obvious anxiety ) ; ( 6 ) Lactating women and women who are preparing for or have become pregnant. ( 7 ) Suspected or had a history of alcohol and drug abuse ; or according to the judgment of the researcher, other situations that reduce the possibility of enrollment or complicate the enrollment, such as frequent changes in the working environment, are likely to cause loss of follow-up. ( Note : Anyone who meets any of the above items is excluded from this topic. )
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM symptom score of functional dyspepsia;Gastric emptying rate;serum calcitonin gene-related peptide;gastrin;Motilin;Somatostatin ( SST );Substance P;5-Hydroxytryptamine;Nipin dyspepsia symptom index;Nipin dyspepsia quality of life index;Hamilton anxiety scale;Efficacy evaluation of functional dyspepsia: effective / ineffective; | — |
Countries
China
Contacts
Public ContactHaoran Chu
The second affiliated Hospital of Anhui University of traditional Chinese Medicine
Outcome results
None listed