Atherosclerotic Cardiovascular Disease
Conditions
Interventions
Exercise:Exercise+Medicine
Control group:Routine Medicine
Sponsors
National Clinical Reasearch Center for Geriatric Diseases, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age = 60 years old 2. Clear awareness, good comprehension, and good language communication skills 3. Compliance of one of the following : ? Diagnosis of stable coronary heart disease:meet with the diagnostic criteria of the Guidelines for Diagnosis and Treatment of Stable Coronary Heart Disease; ? Carotid artery atherosclerosis : Intima-media thickness of carotid artery =0.9 mm or atherosclerotic plaque by carotid ultrasound 4. Not participating in other rehabilitation training programs 5. Voluntarily participate and sign an informed consent form, and are willing to follow the visit plan requirements.
Exclusion criteria
Exclusion criteria: 1. Poor compliance and failure to follow up on time 2. Meet any of the following items: A) Patients with severe arrhythmia, moderate or severe valvular disease, atrial fibrillation, aortic dissection or aneurysm, obstructive hypertrophic cardiomyopathy, and the New York Society of Cardiology (NYHA) =?;B) with mental illness, cognitive insufficiency, visual dysfunction, or auditory impairment who cannot cooperate exercise C) Chronic obstructive pulmonary disease, active pulmonary tuberculosis, pulmonary fibrosis and other chronic pulmonary diseases D) Serious liver, kidney, lung and chest diseases and chronic consumptive diseases such as blood system diseases and cancer E) =50% stenosis of the carotid artery, or stroke or transient ischemic attack at 3 months prior to randomization F) History of aortiti s or immune vasculitis G) Patients in the acute phase of various diseases or with unstable clinical symptoms H) Patients with nerve, muscle and bone diseases, unable to exercise normally I) Serious adverse reactions or significant ECG changes occurred during the exercise endurance test 3. Any other investigator deemed inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse wave velocity; | — |
Secondary
| Measure | Time frame |
|---|---|
| ABI;Cardiovascular hospitalization;MI;TIA/STROKE;all cause death;PVO2;IMT;IL-6;CRP;life quality; | — |
Countries
China
Contacts
Public ContactFeng Cao
Chinese PLA gengeral Hospital
Outcome results
None listed