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Randomized, controlled, multicenter clinical study of rebamipide in the prevention of gout attack

Randomized, controlled, multicenter clinical study of rebamipide in the prevention of gout attack

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078984
Enrollment
Unknown
Registered
2023-12-22
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gout

Interventions

group A: Febuxostat 20 mg bid + rebamipide 0.1 g tid
group B:Febuxostat 20 mg bid + colchicine tablets 0.5 mg qd
groupC:Febuxostat 20 mg bid

Sponsors

Anqing Hospital Affiliated to Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1 ) All enrolled patients met the 1977 American College of Rheumatology ( ACR ) gout classification criteria and / or the 2015 ACR gout classification criteria ; 2 ) At least one gouty arthritis occurred within one year before the study ; 3 ) serum uric acid > 7.0mg / dl ( 420umol / L ) ; 4 ) Not receiving any uric acid-lowering drugs for at least 1 month before entering the study ; 5 ) Included in the study after written informed consent ; 6 ) HLA-5801 was negative.

Exclusion criteria

Exclusion criteria: 1 ) age 1.5 mg / dL ( 133umol / L ) ; 4 ) Patients with severe comorbidities, and researchers judged not to be the appropriate candidates to participate in the study.

Design outcomes

Primary

MeasureTime frame
Blood uric acid;Number of gout attacks;

Countries

China

Contacts

Public ContactWang Guihong

Department of Rheumatology, Anqing Hospital Affiliated to Anhui Medical University

aqfsmy2010@163.com+86 138 6644 9332

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026