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Breast Milk Bacteria: The Key to Diagnosing Defecation Frequency Changes in Infants - A Prospective Cohort Study

The Regulatory Mechanism of Microbiome and Functional Oligosaccharides at Different Stages of Breast Milk Affect the Changes in Infant Defecation Frequency

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078973
Enrollment
Unknown
Registered
2023-12-22
Start date
2020-08-24
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant defecation frequency variations

Interventions

Increased defecation frequency in infants (Those who defecated more than three times per day):N/A
Decreased defecation frequency in infants (Those who defecated more than four days or required assistance):N/A
Average defecation frequency in infants (Those who defecated once within three days or <= three times per day):N/A

Sponsors

The First Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Months to 43 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria for infants were as follows: 1. Age between 1 and 6 months 2. Term infants of average weight 3. No use of probiotics or antibiotics within the previous four weeks The corresponding mothers met the following criteria: 1. Excellent physical and mental health during pregnancy and breastfeeding 2. Healthy breast status 3. No use of probiotics and antibiotics during pregnancy and breastfeeding

Exclusion criteria

Exclusion criteria: The infant exclusion criteria are as follows: 1. There is no infectious diarrhea, biliary diseases, anorectal diseases, congenital neuro-muscular disease, metabolic and endocrine diseases, hereditary diseases, or drug-induced abnormal defecation. 2. Stool frequency and traits must have changed significantly in the two weeks preceding the study. 3. No severe eczema and cow’s-milk protein allergy. The mother exclusion criteria are as follows: (1) Pregnancy complications such as pregnancy diabetes, pregnancy hypertension and hypothyroidism during pregnancy; (2) Allergic diseases; (3) Anemia, malnutrition, etc; (4) Neuropsychiatric disorders; (5) Family inherited diseases; (6) Having bad habits.

Design outcomes

Primary

MeasureTime frame
The relative abuande of human breast milk microbiota;

Countries

China

Contacts

Public ContactYongkun Huang

The First Affiliated Hospital of Kunming Medical University

hykkmyncnwd@163.com+86 135 7709 7854

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026