paroxysmal kinesigenic dyskinesia
Conditions
Interventions
Test Group - High:Ultrasound therapy (1.5 W/cm2)
Test Group - Medium:Ultrasound therapy (1.0 W/cm2)
Test Group - Low:Ultrasound therapy (0.5 W/cm2)
Control Group:No ultrasound therapy
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1) Meeting the diagnostic criteria for primary PKD: Consensus of Chinese experts in the diagnosis and treatment of paroxysmal kinesigenic dyskinesia; 2) = 14 years old and currently exhibiting clinical symptoms; 3) Patients who have not received anti-epileptic drug treatment within 3 months; 4) Cooperate with various examinations during clinical research; 5) Voluntary participation, with the consent of the patient and their family/guardian, and the signing of an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Secondary PKD caused by various factors, such as hyperthyroidism, encephalitis, multiple sclerosis, etc; 2) Patients with underlying diseases and other central nervous system diseases, such as stroke, history of trauma, history of brain tumors, etc. 3) Pregnant and lactating women; 4) Patients with pacemaker implantation; 5) Long term use of anticoagulants, antipsychotic drugs, and other neuropsychotic drugs; 6) Individuals with mental illness, depression, substance dependence, etc. 7) Patients who are unable to communicate with researchers or staff. 8) Simultaneously participating in other clinical researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PKD severity score; | — |
Secondary
| Measure | Time frame |
|---|---|
| High density EEG;adverse event incidence rate; | — |
Countries
China
Contacts
Public ContactLi Cao
Shanghai Sixth People's Hospital
Outcome results
None listed