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A Study on Predicting the Recurrence of Retinal Vein Occlusion Edema in the Recovery Period Based on Wide Angle Multidimensional Imaging and Time Dependent Phenotypic Prediction

A Study on Predicting the Recurrence of Retinal Vein Occlusion Edema in the Recovery Period Based on Wide Angle Multidimensional Imaging and Time Dependent Phenotypic Prediction

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078959
Enrollment
Unknown
Registered
2023-12-21
Start date
2023-12-22
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Vein Occlusion

Interventions

Observation group:Observational studies do not involve intervention

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Qualified participants selected for this study must meet all of the following criteria: 1. Patients diagnosed with RVO-ME receiving anti VEGF treatment through previous fundus examination (aged 18-80 years) 2. Best corrected visual acuity (BCVA) after anti VEGF treatment (Snellen) 20/32 to 20/400 3. Retinal fovea thickness (CST) < 320 µ M (Heidelberg OCT, CST < 300 for other models) µ M) 4. Able to accept follow-up between 12 months 5. Includes OCT image data of patients before treatment

Exclusion criteria

Exclusion criteria: Subjects who meet any of the following criteria are not eligible to be enrolled in this study. 1. Retinal vein occlusion patients with severe cardiovascular and cerebrovascular diseases 2. Pregnant women and lactating patients, children, mental disorders, and individuals with cognitive impairment 3. Iritis discovered under slit lamp, severe ischemic retinopathy 4. RVO-ME patients who received intravitreal corticosteroid injection or laser therapy within the first 6 months of the study

Design outcomes

Primary

MeasureTime frame
ellipsoid crack in OCT images;OCTA Blood flow diameter index at 9mm on the temporal side of the parafovea;

Secondary

MeasureTime frame
Image phenotype information of OCT image markers;Thickness information of various OCT retinal zones;Ischemic imaging phenotype information;

Countries

China

Contacts

Public ContactYupeng Xu

Shanghai General Hospital

kevinxyp@163.com+86 159 2111 1582

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026