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the impact of ropivacaine combined with dexmedetomidine for labor analgesia on postpartum depression

the impact of ropivacaine combined with dexmedetomidine for labor analgesia on postpartum depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078957
Enrollment
Unknown
Registered
2023-12-21
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postpartum depression

Interventions

treatment group:epidural labor analgesia with ropivacaine combined with dexmedetomidine
control group:primiparas who reject epidural labor analgesia have a normal delivery

Sponsors

The First Affiliated Hospital, Jiangxi Medical College, Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1) Cephalic primipar who in line with the diagnostic criteria in labor, and there is no contraindication for epidural analgesia with ropivacaine and dexmedetomidine 2) Age: 20-35 years old. 3) Gestational age: 37-42 weeks. 4) Those with the indication of vaginal trial labor. 5) No history of reproductive tract malformation or uterine disease (such as uterine fibroids, adenomyosis, etc.). 6) There were no medical or surgical complications during the whole pregnancy. 7) No history of alcohol addiction. 8) No previous history of depression and no depression during pregnancy (EPDS score < 10 before delivery). 9) Subjects must voluntarily accept the study with informed consent.

Exclusion criteria

Exclusion criteria: 1) Those who do not meet the inclusion criteria. 2) Position is not normal, such as breech, presentation and persistent occipital transverse surface, after persistent pillow, etc. 3) Multiple pregnancies. 4) Patients with pregnancy complications, such as hypertensive disorders of pregnancy. 5) Patients with fetal distress. 6) Patients with risk factors of prenatal hemorrhage such as placenta previa or placental abruption. 7) Patients with psychosis or previous depression.

Design outcomes

Primary

MeasureTime frame
Edinburgh Postnatal Depression Scale,EPDS;

Secondary

MeasureTime frame
Apgar score of newborns;Early complications in newborns;Postpartum complications during painless delivery;

Countries

China

Contacts

Public ContactWei Zheng

The First Affiliated Hospital, Jiangxi Medical College, Nanchang University

zheng1989wei@qq.com+86 187 7003 1135

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026