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The correlation between C-reactive protein gene polymorphism and Helicobacter pylori associated chronic gastritis, tongue coating inflammation cell level, and traditional Chinese medicine syndrome

The correlation between C-reactive protein gene polymorphism and Helicobacter pylori associated chronic gastritis, tongue coating inflammation cell level, and traditional Chinese medicine syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078950
Enrollment
Unknown
Registered
2023-12-21
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori associated Gastritis

Interventions

Observation group (subjects with Hp positive):None
Control group (subjects with Hp negative):None

Sponsors

Shenzhen TCM anorectal hospital (Futian)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age range: 18~75 years old; (2) Those who meet the diagnostic criteria for Hp infection, refer to the diagnostic criteria of the "Fifth National Consensus Report on the Treatment of Helicobacter pylori Infection" formulated by the Helicobacter pylori and Peptic Ulcer Group of the Chinese Society of Gastroenterology in 2017, and have not been radically cured in the past; (3) The results of endoscopic and pathological examinations in the past six months meet the diagnostic criteria for chronic gastritis, with reference to the "Chinese Consensus Opinions on Chronic Gastritis" formulated by the Gastroenterology Branch of the Chinese Medical Association in 2017; (4) Actively cooperate with the collection of clinical information and data of the four diagnoses of traditional Chinese medicine, gastroscopy and pathological examination, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Under 18 years old or over 75 years old; (2) Use of antibiotics, antacids, probiotic preparations, etc. in the past 1 month; (3) Colonoscopy and/or enema treatment in the past 1 month; (4) Inflammatory bowel disease, peptic ulcer, gastrointestinal bleeding, chronic pancreatitis, liver cirrhosis and other digestive system diseases, as well as thyroid diseases, scleroderma, metabolic syndrome, diabetes, coronary heart disease, Parkinson's disease, etc.; (5) Previous gastrointestinal or abdominal surgery; (6) Combined tumors, intestinal tuberculosis, immunodeficiency and other diseases; (7) Those with serious infections in other parts; (8) Combined with severe cardiovascular and cerebrovascular, blood system, respiratory system, urinary system, endocrine system and other serious diseases; (9) Pregnant or lactating women; (10) Incomplete information affects judgment; (11) Patients who are unable to cooperate.

Design outcomes

Primary

MeasureTime frame
Single nucleotide polymorphism of different loci in C-reactive protein gene;histomorphology of gastric mucosa;traditional Chinese medicine syndrome;

Secondary

MeasureTime frame
Inflammatory cell level of tongue coating;

Countries

China

Contacts

Public ContactWeiming Kuang

Shenzhen TCM anorectal hospital (Futian)

drkuangwm@163.com+86 158 7658 5642

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026