Rosacea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Case group: Inclusion criteria: 1) Patients diagnosed with rosacea who meet the diagnostic criteria of the National Rosacea Expert Committee (2017 edition); Diagnosed by two senior dermatologists; The history was longer than 1 year 2) Age 18-60 3) Han Nationality 4) Primary school education or above; 5) Right-handed 6) Sign informed consent Note: Patients who meet the above 6 criteria at the same time can be included in this study (2) Control group: The healthy control group was included from the faculty, graduate students and social recruiters, and gender, age and education level were matched. Inclusion criteria 1) No history of rosacea and related symptoms 2) Age 18-60 3) Han Nationality 4) Primary school education or above 5) Right-handed 6) I voluntarily participate and sign the informed consent Note: Healthy subjects who meet the above 6 criteria can be included in this study.
Exclusion criteria
Exclusion criteria: Case group exclusion criteria: 1) Age Sixty years old 2) Serious primary diseases of the heart, liver, kidney, blood, nervous system (such as migraine, glioma, epilepsy, etc.) 3) Meet the DSM-IV diagnostic criteria or mental illness (e.g., schizophrenia, anxiety disorder, depression disorder, bipolar disorder, etc.) 4) Have taken pesticides, poisons or other substances that may cause damage to the central nervous system, and have a history of alcohol and drug abuse 5) Self-administered antidepressant or other psychiatric drugs; 6) Patients who have taken oral psychotropic drugs such as pregabalin and carvedilol within 2 weeks; 7) Pregnant and lactating patients. Note: All patients meeting the above criteria were excluded Control group exclusion criteria 1) Age Sixty years old 2) Serious primary diseases of the heart, liver, kidney, blood, nervous system (such as migraine, glioma, epilepsy, etc.) 3) Pregnant and lactating patients. 4) Serious asymmetry or clear lesions in the skull anatomy found in the scan; 5) Unclear consciousness, unable to express discomfort symptoms independently or unable to cooperate with the completion of this study. Note: Healthy subjects who meet any 1 of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxyhemoglobin;Deoxyhemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Verbal Fluency Task performance; | — |
Countries
China
Contacts
West China Hospital, Sichuan University