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Prospective study of gold bifidum combined with montmorillonite powder in perioperative intestinal mucosal barrier protection in patients with colorectal cancer

Prospective study of gold bifidum combined with montmorillonite powder in perioperative intestinal mucosal barrier protection in patients with colorectal cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078918
Enrollment
Unknown
Registered
2023-12-21
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Experimental group:Gold bifidus and montmorillonite powder were added on the 1st, 2nd, 3rd and 4th days after surgery (gold bifidus (2g once three times a day), montmorillonite powder (once a bag thre
Control group:Conventional treatment

Sponsors

The First People's Hospital of Shuangliu District, Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 30 ~ 80 years old. (2) American Society of Anesthesiologists (ASA) Grade I to II. (3) Biopsy results confirmed colorectal malignancy. (4) There was no evidence of widespread metastasis. (5) Laparoscopic colorectal resection was performed with the patient's consent. (6) Obtain the consent of patients to conduct this study, and the compliance is good.

Exclusion criteria

Exclusion criteria: (1) There are contraindications of laparoscopic surgery (such as extensive intraperitoneal adhesion, etc.). (2) Emergency surgery. (3) There were obvious manifestations of intestinal obstruction or intestinal paralysis before surgery. (4) The tumor is not resectable. (5) Conversion to open surgery. (6) Reoperation within a short period (within 15d). (7) Persistent uncorrected water and electrolyte disturbances (such as hypokalemia, hypomagnesia, etc.). (8) Those who have used similar drugs such as Smecta and gold bifidus during the same period. (9) Unwilling to participate in the study.

Design outcomes

Primary

MeasureTime frame
Serum D-lactic acid ;hemoendotoxin;Plasma diamine oxidase (DAO) activity;tumor necrosis factor a;Interleukin-1;Postoperative recovery of gastrointestinal function;

Secondary

MeasureTime frame
Incidence of postoperative infectious complications;Postoperative recovery;

Countries

China

Contacts

Public ContactYONG YANG

The First People's Hospital of Shuangliu District, Chengdu

88499353@qq.com+86 133 0807 0645

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026