depth of anesthesia and noxious stimulation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged 0-12 years old, undergoing elective non-cardiac surgery under general anesthesia; (2) On the day of surgery, the corrected gestational age is = 37 weeks; (3) ASA I-III level; (4) The expected anesthesia time (defined as the time from anesthesia induction to cessation of using anesthetic drugs) is greater than 30 minutes; (5) Obtaining permission from parents or guardians (signing informed consent form)
Exclusion criteria
Exclusion criteria: (1) Born with congenital malformations or other diseases that may affect brain development (such as neonatal hypoxic-ischemic encephalopathy, genetic diseases, chromosomal diseases, etc.); (2) Suffering from neurological, psychiatric, or severe cardiovascular diseases (such as complex congenital heart disease, cyanotic congenital heart disease); (3) The EEG monitoring site conflicts with the surgical disinfection site; (4) Long term treatment with sedatives (such as propofol, midazolam, dexmedetomidine, ketamine, etc.), opioid drugs (such as morphine, fentanyl, etc.), or antipsychotic drugs; (5) Known to have allergies or adverse reactions to EEG or ECG electrode adhesives; (6) Children who are not suitable for receiving inhalation anesthesia (such as a family history of malignant hyperthermia, need for intraoperative neurological function monitoring, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG features related to different levels of consciousness;EEG features related to noxious stimulations; | — |
Secondary
| Measure | Time frame |
|---|---|
| EEG features related to age;EEG features related to types of anesthetic; | — |
Countries
China
Contacts
West China Hospital, Sichuan University