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Development and validation of electroencephalogram-based prediction models for the depth of anesthesia and noxious stimulation in children

Development and validation of electroencephalogram-based prediction models for the depth of anesthesia and noxious stimulation in children

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078859
Enrollment
Unknown
Registered
2023-12-20
Start date
2023-12-25
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depth of anesthesia and noxious stimulation

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 12 Years

Inclusion criteria

Inclusion criteria: (1) Aged 0-12 years old, undergoing elective non-cardiac surgery under general anesthesia; (2) On the day of surgery, the corrected gestational age is = 37 weeks; (3) ASA I-III level; (4) The expected anesthesia time (defined as the time from anesthesia induction to cessation of using anesthetic drugs) is greater than 30 minutes; (5) Obtaining permission from parents or guardians (signing informed consent form)

Exclusion criteria

Exclusion criteria: (1) Born with congenital malformations or other diseases that may affect brain development (such as neonatal hypoxic-ischemic encephalopathy, genetic diseases, chromosomal diseases, etc.); (2) Suffering from neurological, psychiatric, or severe cardiovascular diseases (such as complex congenital heart disease, cyanotic congenital heart disease); (3) The EEG monitoring site conflicts with the surgical disinfection site; (4) Long term treatment with sedatives (such as propofol, midazolam, dexmedetomidine, ketamine, etc.), opioid drugs (such as morphine, fentanyl, etc.), or antipsychotic drugs; (5) Known to have allergies or adverse reactions to EEG or ECG electrode adhesives; (6) Children who are not suitable for receiving inhalation anesthesia (such as a family history of malignant hyperthermia, need for intraoperative neurological function monitoring, etc.).

Design outcomes

Primary

MeasureTime frame
EEG features related to different levels of consciousness;EEG features related to noxious stimulations;

Secondary

MeasureTime frame
EEG features related to age;EEG features related to types of anesthetic;

Countries

China

Contacts

Public ContactZuo Yunxia

West China Hospital, Sichuan University

zuoyunxia@scu.edu.cn+86 189 8060 1541

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026