The mechanism of arecaine induced oral submucosal fibrosis mediated by ubiquitization of epigenetic crosstalk inhibited VHL transcription

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300078834

Enrollment

Unknown

Registered

2023-12-19

Start date

2024-01-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral submucous fibrosis

Interventions

OSF Group:NA

Control group:NA

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: OSF patient and healthy patient

Exclusion criteria

Exclusion criteria: Patients who did not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Expression levels of PCR detection of a-SMA, COL1A1, FN1 in tissues;	—

Countries

China

Contacts

Public ContactLuo Wen

The First Affiliated Hospital of Hainan Medical College

luowen228@163.com+86 151 0366 0395

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026