Multi-modal magnetic resonance imaging-based study in the effects and rehabilitation mechanisms of cognitive-motor dual-task training to improve age-related cognitive impairment

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300078826

Enrollment

Unknown

Registered

2023-12-19

Start date

2023-12-20

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

age-related cognitive impairment

Interventions

Cognitive training group:Computerized cognitive function training. The training system is a game-based interactive cognitive and mental state intelligent training mode based on the classic paradigm of

Motor training group:subjects received 30 minutes of resistance treadmill training. The treadmill resistance is dynamically adjusted according to the experience of the subject and determined by the to

Cognitive motor dual-task training group:Cognitive training and motor training were conducted at the same time.

Control group:Health education shall be given with the same frequency as training, and the content shall be health propaganda unrelated to cognition, in the form of teleconference.

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Meet the diagnostic criteria of aging-related cognitive impairment; ? Age = 65 years; ? Right handedness; ? The mother tongue is Chinese; ? Can participate in sports and cognitive training as required; ? Voluntarily participated in this study and signed the informed consent.

Exclusion criteria

Exclusion criteria: ? History of neuropsychiatric disease was present; ? Patients with serious digestive system diseases, immune function abnormalities, and serious diseases of heart, liver, lung, and kidney; ? MRI contraindications exist; ? Severe visual and hearing impairment, accompanied by major physical diseases, etc., led to communication difficulties, and could not participate in the screening; ? Currently taking drugs that affect cognitive function; ? Have participated in or are participating in other clinical trials related to cognitive function within one year.

Design outcomes

Primary

Measure	Time frame
MoCA;AVLT-H;	—

Secondary

Measure	Time frame
MMSE;STROKE;STT-A;DST;STT-B;SDMT;IADL;SF-36 quality of life questionnaire;MRI/ fMRI;	—

Countries

China

Contacts

Public ContactWei-Jun Gong

Beijing Rehabilitation Hospital, Capital Medical University

gwj197104@ccmu.edu.cn+86 132 4047 3005

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026