Epilepsy
Conditions
Interventions
Stimulation group:Ultrasound stimulates the left cervical vagus nerve
Pseudostimulus group:A special sham stimulation probe stimulates the vagus nerve in the left neck
Sponsors
Zhujiang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Male or female aged = 18 and = 60 years old; 2) Diagnosis of drug-refractory epilepsy; 3) The subject or his guardian can understand the purpose of the trial, adhere well to the trial protocol, voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Suffering from mental illness and unable to cooperate with treatment; 2) Accompanied by intrauterine distress, obstructed labor, cerebral hemorrhage and other diseases that may lead to secondary epilepsy; 3) Severe cardiovascular and cerebrovascular diseases, severe liver and kidney dysfunction and other systemic diseases that seriously affect health; 4) Women who are pregnant or intend to become pregnant, lactating women; 5) Neck trauma, skin ulceration and abnormal structure of blood vessels in the neck; 6) Those who the investigator believes that it is not suitable to participate in clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| electroencephalographicchanges;Seizure conditions;vital signs; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep-time slow-wave index (SDI);Quality of Life Score;Severity of epilepsy; | — |
Countries
China
Contacts
Public ContactYanwu Guo
Zhujiang Hospital
Outcome results
None listed