elderly patients with mechanical ventilation
Conditions
Sponsors
The First Aftiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? Aged from 65 years old to 85 years old ? Patients with mechanical ventilation ? Sign an informed consent form
Exclusion criteria
Exclusion criteria: ? Pregnancy or breastfeeding ? Severe pre-existing parenchymal liver disease with clinically significant portal hypertension Child-Pugh grade C cirrhosis or acute liver failure ? Severe head injury Brain tumor increased intracranial pressure increased cerebrovascular accidental coma, status epilepticus, etc. ? Patients with a history of alcohol or substance abuse ? Patients requiring deep sedation (RASS<-2) depending on the clinical consideration of the condition ? Severe arrhythmias (eg, third-degree AV block with no pacemaker sinus bradycardia<50 beats/min) ? Patients with allergies to remazolam benzodiazepines ? Patients who are unable to obtain informed consent ? He is participating in other relevant clinical drug validation studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation compliance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation onset time;Wake-up time after deactivation;Mechanical ventilation time;Length of ICU hospital stay;Incidence of delirium;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactJun Wang
The First Aftiliated Hospital of Soochow University
Outcome results
None listed