Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) All patients diagnosed with osteoarthritis (OA) and undergoing primary unilateral total knee arthroplasty; (2) age 18-80 years; (3) preoperative American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) of grade I-III
Exclusion criteria
Exclusion criteria: (1) preoperative anemia or blood system diseases, baseline hemoglobin lower than 11 g/dL; (2) long-term use of anticoagulants; (3) preoperative lower limb vascular disease; (4) poor compliance; (5) high-risk medical comorbidities (liver and kidney function diseases); (6) revision surgery; (7) history of major knee surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total blood loss;Blood transfusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| occult blood loss;Intraoperative blood loss;Incidence of postoperative complications;Indicator of inflammation level;Visual analogue scale pain score;Range of knee motion;Lower Limb Diameter (Perimeter of the Patellar); | — |
Countries
China
Contacts
West China Hospital, Sichuan University