chronic constipation
Conditions
Interventions
Experimental group :none
Control group:none
Sponsors
Army Medical Center( Daping Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients gave informed consent and volunteered to participate in this study; (2) Male or female, subject age between 18 and 70 years old; (3) Healthy subjects: asymptomatic healthy individuals; (4) Chronic constipation patients: meeting the Rome IV diagnostic criteria for functional constipation and the diagnostic criteria for pelvic floor functional defecation disorders; (5) No history of rectal-anal surgery, untreated by medication or poorly treated by medication.
Exclusion criteria
Exclusion criteria: (1) Subject age = 18 years or subject age = 70 years; (2) Definite cause of secondary constipation and pharmacogenetic constipation; (3) Atopic infections (e.g., tuberculosis, Crohn's disease, ulcerative colitis, etc.); (4) Organic diseases of the gastrointestinal tract or other systemic diseases involving the gastrointestinal tract, such as neuromuscular lesions, endocrine and metabolic diseases, systemic sclerosis, and neurological diseases; (5) Those with a combination of serious primary diseases of the cardiovascular, cerebrovascular, hepatic, renal, respiratory and hematopoietic systems, malignant tumors and/or other progressive underlying diseases; (6) Women who are pregnant, lactating, or in a special physiological cycle; (7) Uncooperative or mentally abnormal patients; (8) Patients with other factors that may affect the results of the study or who, in the judgment of the investigator, should not be admitted to the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation Rating System Scale;Visual Analog Scale for Pain;Patient Assessment of Quality of Life Questionnaire for Constipation;Fecobionics evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anorectal manometry;Defecography; | — |
Countries
China
Contacts
Public ContactYang Min
Army Medical Center
Outcome results
None listed