surgery requiring tracheal intubation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.age 18-65 years. 2.American Society of Anesthesiologists (ASA) physical status I to II. 3.body mass index (BMI) 18-28 kg/m2. 4.Mallampati classification I to II. 5.scheduled for elective non-cardiac surgery under general anesthesia with single-lumen tracheal intubation. 6.informed consent form signed by the patient or authorized person.
Exclusion criteria
Exclusion criteria: 1.with abnormal hemodynamic parameters, including baseline blood pressure (BP)>180/110mmHg, systolic blood pressure (SBP)6 or GFR 5.5 mmol/L) within 48 hours, or taking hormones or other immunosuppressive agents for more than 10 days within six months or a history of adrenocortical suppression or immune system disorders. 11.history of drug or alcohol abuse or use of sedatives or narcotics in the past 24 hours. 12.participate in other drug trial within 3 months. 13.allergic to test drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation condition score;blood pressure;heart rate;Adrenergic response at intubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of lighted stylet intubation attempts;the rate of successful lighted stylet intubation on the first attempt ;Number of transfers to other methods of ventilation; | — |
Countries
China
Contacts
China-Japan Union Hospital of Jilin University