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Research on the causes and treatment of burning mouth syndrome

Study on the relieving effect of caffeine on clinical symptoms of burning mouth syndrome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078771
Enrollment
Unknown
Registered
2023-12-18
Start date
2024-01-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burning mouth syvdrome

Interventions

Caffeine Group:Participants consumed commercial instant coffee containing 120-150 mg of caffeine daily between 8:00 AM and 12:00 PM for two weeks.
Alpha-Lipoic Acid (ALA) Group:Participants were administered 200 mg of ALA three times daily after meals for two weeks.
Psychological counseling group:Provide BMS disease explanation and psychological counseling for patients.

Sponsors

West China Hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria • Adults over 18 years of age • Diagnosis of BMS according to the 3rd edition of the International Classification of Headache Disorders (ICHD-3) • Daily intraoral burning or dysaesthesia lasting for more than 2 hours for over 3 months • Normal oral mucosa and sensory testing • Condition not better accounted for by another ICHD-3 diagnosis

Exclusion criteria

Exclusion criteria: Participants were excluded if they met any of the following criteria: 1. Secondary BMS due to local or systemic disorders 2. Prior treatment for BMS 3. Psychiatric or progressive neurological disorders 4. Systemic disorders potentially associated with oral disease 5. Long-term history of smoking, drinking, or medication use 6. Consumption of caffeinated products 7. Poor oral hygiene 8. Abnormal blood test results (including blood count, glucose, serum iron, ferritin and transferrin, folic acid, or vitamin B12 levels) 9. Incomplete medical records 10. Unwillingness to participate

Design outcomes

Primary

MeasureTime frame
Visual Analogu Scale;

Countries

China

Contacts

Public ContactLu Jiang

West China Hospital of Stomatology, Sichuan University

jianglu@scu.edu.cn+86 159 2851 9595

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026