Sepsis
Conditions
Interventions
Experimental group: Patients with II/R complicated with sepsis during the perioperative period of retroperitoneal tumors:None
Control group: Patients with II/R of retroperitoneal tumors during the perioperative period but without concurrent sepsis:None
Sponsors
Jinshan Hospital,FudanUniversity
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) sign the informed consent form. 2) Age > 18 years old. 3) abdominal surgery was performed in our hospital from January 2023 to June 2026 to treat perioperative patients with II/R. II/R patients meet one of the following criteria: a) persistent shock: norepinephrine dose > 0.2 µ g / kg/min > 48hb) bleeding is greater than 1000mlc) intestinal failure: paralytic intestinal obstruction > 24 hours and d) newly developed organ failure (at least 2 of the following 6 criteria): increased dose of vasopressor, elevated serum lactate, decreased oxygenation index, and new renal replacement therapy. Bilirubin and international standardized ratio (INR) increased, or all of the following increased: alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH).
Exclusion criteria
Exclusion criteria: 1) the life expectancy of patients is less than 48 hours. 2) pregnant and lactating women. 3) any active autoimmune disease or history of autoimmune disease. 4) there are factors of human immunodeficiency virus infection, other immunosuppression or deficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbiome;specificity;sensibility; | — |
Countries
China
Contacts
Public ContactLin Zhang
Jinshan Hospital,FudanUniversity
Outcome results
None listed