urinary incontinence
Conditions
Interventions
Urinary incontinence group:Treatment Group: Apply testosterone cream to the vaginal wall, with a dosage of 0.5g each time, twice a week for a total of 10 times. Concurrently, conduct pelvic floor musc
Control group: N/A
Sponsors
Hainan Western central Hospital
Eligibility
Sex/Gender
Female
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Urinary incontinence group: postmenopausal women with clinically diagnosed SUI; Healthy control group: postmenopausal healthy female volunteers recruited during the same period, no benign gynecological diseases, no evidence of stress incontinence and female pelvic floor dysfunction;
Exclusion criteria
Exclusion criteria: 1) had undergone stress incontinence surgery or had a history of stress incontinence surgery, 2) had undergone abdominal or pelvic surgery within the first 6 months of enrolment, 3) had a urinary tract infection, 4) had a history of neurological or psychiatric disorders, 5) had uncertain menopausal status, 6) had been diagnosed with urge incontinence or mixed incontinence, 7) had cancer, 8) had vaginal bleeding with an unknown history, 9) Receiving systemic or local hormone therapy (including oral contraceptives and vaginal estrogen use, ingestion of selective estrogen receptor or androgen receptor modulators), and 10) being unable to read and sign informed consent forms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum total testosterone;Serum free testosterone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex hormone-binding globulin;Free testosterone/total testosterone ratio;Free testosterone index;Serum deoxyepiandrosterone levels;Serum androstenedione levels; | — |
Countries
China
Contacts
Public ContactYingxiu Chen
Hainan Western central Hospital
Outcome results
None listed