Sarcopenia
Conditions
Interventions
Control group:habitual diet
Low dose intervention group:Miaokelanduo original cheese slices intake+habitual diet
High dose intervention group:Miaokelanduo gold cheese slices intake+habitual diet
Sponsors
Soochow University
Eligibility
Sex/Gender
Female
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Initial screening: 1) 60-80 years old, female; 2) Female calf circumference<33cm or SARC CalF score = 11. Re screening: 1) Decreased muscle strength (grip strength: female<18kg) and/or decreased physical function (5 sit ups for = 12s). 2) Irregularly taking nutritional supplements such as vitamin D, calcium tablets, protein powder, and fish oil.
Exclusion criteria
Exclusion criteria: Initial screening: 1) Obese individuals have a BMI of = 28 kg/m2; 2) Severe lactose intolerance and regular cheese consumers; 3) Action ability or cognitive impairment; 4) There are diabetes, severe hypertension, decompensation of liver function, serious impairment of renal function (CrCl<30mL/min), tumors, cardiopulmonary insufficiency, gastrointestinal absorption dysfunction and other diseases; 5) Unable to complete follow-up after living outside for 3 months; 6) Wear a pacemaker, stent, intrauterine device, etc. Re screening: 1) Unsigned informed consent form; 2) Moderate intensity aerobic activity for at least 150 minutes or 75 minutes per week, intense intensity aerobic activity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| grip strength;5 sitting times;6m walking time;balance test;SMI;calf circumference; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin-like growth factor 1;Free L-carnitine;total carnitine;C reactive protein;interleukin 6;Creatinine/Cystatin C; | — |
Countries
China
Contacts
Public ContactJingsi Chen
Soochow University
Outcome results
None listed