anesthesia
Conditions
Interventions
P group:Induction and maintenance of anesthesia using propofol
EP group:Induction and maintenance of anesthesia using a mixture of propofol and etomidate
R group:Induction and maintenance of anesthesia using remimazolam
Sponsors
Stomatological Hospital Affiliated to Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: ?Young adults aged 18-40 years old ?Healthy patients with ASA classification I, body mass index 20-30kg/m2, scheduled for elective maxillofacial surgery (within 3 hours) ?No severe hearing, language, visual and motor impairments before surgery , there was no history of taking psychotropic drugs within six months before this admission.
Exclusion criteria
Exclusion criteria: ? Those with severe cardiopulmonary disease or liver and kidney dysfunction ? Allergic to study-related drugs ? Those with central nervous system disease or mental illness, long-term use of sedatives or antidepressants, and a history of alcohol abuse or addiction; ? Refuse to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Raw EEG features during surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient baseline date;Hemodynamic data during the surgery;intraoperative adverse events;Decrease in SpO2 value during induction of anesthesia;Operation time, anesthesia time, and time to withdraw endotracheal tube after drug withdrawal;PSI value during extubation; | — |
Countries
China
Contacts
Public ContactYU CONG
Stomatological Hospital Affiliated to Chongqing Medical University
Outcome results
None listed