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The role of different subpopulations of myeloid-derived suppressor cells (MDSCs)  in secondary Persistent Inflammation, Immunosuppression, and Catabolism Syndrome(PICS)in critically ill patients

The role of different subpopulations of myeloid-derived suppressor cells (MDSCs)  in secondary Persistent Inflammation, Immunosuppression, and Catabolism Syndrome(PICS)in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078713
Enrollment
Unknown
Registered
2023-12-15
Start date
2023-12-20
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

PICS group:None
non PICS group:None

Sponsors

Hebei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age = 18 years old; Acute Physiology and Chronic Health Evaluation II (APACHE II) = 15 points; Agree to participate in this study.

Exclusion criteria

Exclusion criteria: Pregnant women, cancer patients, transplant patients, HIV infected individuals, or patients receiving immunosuppressive therapy.

Design outcomes

Primary

MeasureTime frame
M-MDSCs;PMN-MDSCs;—

Secondary

MeasureTime frame
Lymphocyte subpopulation count;regulatory T-cell;cytokine;ARG-1;iNOS;—

Countries

China

Contacts

Public ContactLijing Jia

Hebei General Hospital

jlj011365@163.com+86 153 7382 9696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026