Cardiovascular responses to tracheal intubation
Conditions
Interventions
Older age group:The initial infusion dose of cyclopofol was 0.3mg/kg in the elderly group and pumped at a rate of 200ml/h. If the patient s tracheal intubation response was positive, the next patient
Non-elderly group:The initial infusion dose of cypofol was 0.4mg/kg in the non-elderly group and pumped at a rate of 200ml/h. If the patient s tracheal intubation response was positive, the next patie
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1) Age =18 years, =89 years; 2) General anesthesia double-cavity tracheal intubation was performed at selected time; 3)ASA grade I-III; 4) Voluntarily sign informed consent;
Exclusion criteria
Exclusion criteria: 1) Previous history of poor anesthesia, such as anesthesia allergy or malignant hyperthermia; 2) cyclopofol allergy; 3) Body mass index is too high or too low, such as IBM > 30kg/m2 or 120 times/min or HR < 60 times/min); 6) Apnea, history of difficulty intubation, or preoperative evaluation of suspicious difficult airway; 7) High risk of reflux aspiration; 8) Severe abnormal liver and kidney function (Child-PughC grade, preoperative dialysis); 9) Communication barriers, inability to cooperate, such as language comprehension disorders, mental illness, etc.; 10) History of drug use or drug abuse; 11) Hypertension that was difficult to control before surgery, and SBP=180mmHg or/and DBP=110mmHg; 12) Refusal to participate in the experiment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bispectral index;Cyclopofol dosage;Adverse reaction; | — |
Countries
China
Contacts
Public ContactJiaqiang Zhang
Henan Provincial People's Hospital
Outcome results
None listed