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Clinical observation of Wushen Oral Liquid combined with metoprolol in the treatment of Ventricular Precontraction after PCI for myocardial infarction of qi-yin deficiency type

Clinical observation of Wushen Oral Liquid combined with metoprolol in the treatment of Ventricular Precontraction after PCI for myocardial infarction of qi-yin deficiency type

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078704
Enrollment
Unknown
Registered
2023-12-15
Start date
2023-12-15
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arrhythmia

Interventions

Treatment group:Wushen Oral Liquid combined with metoprolo
Control group:metoprolo

Sponsors

Shuguang Hospital affiliated to Shanghai University of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 85 Years

Inclusion criteria

Inclusion criteria: Myocardial infarction meets the relevant criteria in "Practical Internal Medicine" and the 2019 Chinese Medical Association "Primary Diagnosis and Treatment Guidelines for ST-Segment Elevation Myocardial Infarction". The diagnosis of ventricular premature contraction meets the relevant criteria in the "Chinese Expert Consensus on Ventricular Arrhythmias Primary Version" of the Chinese Society of Cardiac Pacing and Electrophysiology in 2022, and the severity of the condition is graded according to Myerburg frequency =3 and morphology A-C; Aged 25 to 85, gender unrestricted; Acute phase undergoing PCI for revascularization; Disease duration from 2 weeks to 2 years after myocardial infarction; During the clinical observation period, the subjects will stop taking any other similar Chinese herbal medicine or proprietary Chinese medicine; The subjects voluntarily participate in this study, are able to cooperate with clinical observation, and sign a written informed consent form; Subjects who have not participated in any drug clinical trials in the 3 months before enrollment.

Exclusion criteria

Exclusion criteria: Severe primary arrhythmia, severe cardiopulmonary insufficiency, severe neurocirculatory dystonia, and hyperthyroidism; Severe hypertension, severe cardiopulmonary insufficiency (heart failure NYHA grade IV); Poorly controlled severe primary diseases of the liver, kidney, endocrine, respiratory, hematopoietic systems, etc.; Severe infections and advanced malignant tumors; Pregnant or lactating women; Individuals with known allergies or hypersensitivity to the components of the test drug.

Design outcomes

Primary

MeasureTime frame
QT dispersion;

Secondary

MeasureTime frame
The number of premature ventricular beats;Heart rate variability;TNF-a;IL-6;hs-CRP;NO;TCM syndrome score;

Countries

China

Contacts

Public ContactTao Liyu

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

taoliyu37@163.com+86 135 2499 3507

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026