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A prospective randomized controlled study of pulmonary rehabilitation training combined with individualized nutritional intervention to improveclinical outcomes in patients with non-small cell lung cancer

A prospective randomized controlled study of pulmonary rehabilitation training combined with individualized nutritional intervention to improveclinical outcomes in patients with non-small cell lung cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078681
Enrollment
Unknown
Registered
2023-12-15
Start date
2022-01-26
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Control group:The patients were given routine preoperative preparation and education, the operation was carried out according to the plan, and the patients were given routine treatment and education a
Experimental Group:Two weeks before surgery, patients began pulmonary rehabilitation training, and nutritional counseling and dietary guidance were given by nutritionists. According to the reference s

Sponsors

People's Hospital of Chongqing Banan District
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :(1) primary non-small cell lung cancer confirmed by pathological diagnosis; (2) high suspicion of lung cancer based on imaging findings without pathological diagnosis; (3) According to the Chinese guidelines for the diagnosis and treatment of lung cancer, there are indications for thoracoscopic lobectomy and systematic lymph node dissection, and no surgical contraindications were found through routine examination; (4) at least one high risk factor: ? age =75 years or smoking =400 years/cigarette; ? Male age >60 years old with smoking; ? women over 70 years old with smoking history; ? Pulmonary function test showed at least one of the following: forced expiratory volume in 1 second (FEV1) < 1.0L; FEV1/FVC < 50%; Peak expiratory flow (PEF) <250 L/min; ? Bronchial dilation test was positive; (5) Patients agreed to participate in this study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: Exclusion criteria: (1) The results of intraoperative frozen section or postoperative paraffin pathological examination did not meet the diagnosis of primary non-small cell lung cancer; (2) those who were evaluated as unsuitable for thoracoscopic surgery or were converted to thoracotomy; (3) Combined lobectomy, pneumonectomy or pulmonary artery and bronchial sleeve lobectomy were needed during the operation. (4) intraoperative blood loss more than 1000 ml; (5) patients with unplanned reoperation during the study period; (6) those who do not cooperate with pulmonary rehabilitation training or refuse to implement nutrition plan; (7) complicated with severe hepatic and renal insufficiency, intestinal obstruction, gastrointestinal bleeding, etc. (8) participating in other clinical investigators; (9) those who refused to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Functional Assessment of Cancer Treatment-Lung, FACT-L;

Secondary

MeasureTime frame
Pulmonary function;6-minute walk distance 6MWD;patient-generated subjective global assessment;Postoperative pulmonary complications;Protein indicators(TPALBHB);

Countries

China

Contacts

Public ContactJianjun Li

People's Hospital of Chongqing Banan District

676349171@qq.com+86 158 2594 0185

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026