lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria :(1) primary non-small cell lung cancer confirmed by pathological diagnosis; (2) high suspicion of lung cancer based on imaging findings without pathological diagnosis; (3) According to the Chinese guidelines for the diagnosis and treatment of lung cancer, there are indications for thoracoscopic lobectomy and systematic lymph node dissection, and no surgical contraindications were found through routine examination; (4) at least one high risk factor: ? age =75 years or smoking =400 years/cigarette; ? Male age >60 years old with smoking; ? women over 70 years old with smoking history; ? Pulmonary function test showed at least one of the following: forced expiratory volume in 1 second (FEV1) < 1.0L; FEV1/FVC < 50%; Peak expiratory flow (PEF) <250 L/min; ? Bronchial dilation test was positive; (5) Patients agreed to participate in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) The results of intraoperative frozen section or postoperative paraffin pathological examination did not meet the diagnosis of primary non-small cell lung cancer; (2) those who were evaluated as unsuitable for thoracoscopic surgery or were converted to thoracotomy; (3) Combined lobectomy, pneumonectomy or pulmonary artery and bronchial sleeve lobectomy were needed during the operation. (4) intraoperative blood loss more than 1000 ml; (5) patients with unplanned reoperation during the study period; (6) those who do not cooperate with pulmonary rehabilitation training or refuse to implement nutrition plan; (7) complicated with severe hepatic and renal insufficiency, intestinal obstruction, gastrointestinal bleeding, etc. (8) participating in other clinical investigators; (9) those who refused to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Assessment of Cancer Treatment-Lung, FACT-L; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function;6-minute walk distance 6MWD;patient-generated subjective global assessment;Postoperative pulmonary complications;Protein indicators(TPALBHB); | — |
Countries
China
Contacts
People's Hospital of Chongqing Banan District