trigeminal neuralgia
Conditions
Interventions
Healthy group:Transcutaneous vagus nerve stimulation
pain group:Transcutaneous vagus nerve stimulation
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Patients with neuropathic pain diseases (such as trigeminal neuralgia, cervical spondylosis, lumbar spondylosis, post herpetic neuralgia, etc.) or healthy people (2) age 18-70 (3) voluntary cooperation with experimental operation and scale filling (4) BMI between 18.5-30kg/m ²
Exclusion criteria
Exclusion criteria: (1) There are some diseases that affect the measurement of pain, such as limb paresthesia (2) taking some drugs that affect the experiment 24 hours before the test, such as pain relief or sedative hypnotic drugs (3) coagulation dysfunction, patients with bleeding tendency (4) patients with poor sleep quality or mental distress such as anxiety and depression (5) patients with previous allergic events and mental illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of individual pain threshold after transcutaneous vagus nerve stimulation;Changes of individual CPM efficiency values before and after transcutaneous vagus nerve stimulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure, heart rate, oxygen saturation, respiratory rhythm and other vital signs of the subject during stimulation;;Pittsburgh sleep quality index ;Anxiety and Depression Rating Scale; Pain catastrophization scale;Pupil diameter; | — |
Countries
Zhong Guo
Contacts
Public ContactKang Fang
Department of Anesthesiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Outcome results
None listed