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The Effects of Network Transcranial Direct Current Stimulation on exercise-induced hypoalgesia in healthy individuals: A resting-state EEG study

The Effects of Network Transcranial Direct Current Stimulation on exercise-induced hypoalgesia in healthy individuals: A resting-state EEG study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078661
Enrollment
Unknown
Registered
2023-12-14
Start date
2024-01-01
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

HD-tDCS stimulation group:2mA anodic transcranial direct current stimulation in the left primary motor cortex combined with moderate-intensity aerobic exercise
Network-tDCS stimulation group:4mA anodic transcranial direct current stimulation in the left primary motor cortical network region combined with moderate-intensity aerobic exercise

Sponsors

The Sixth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-40 years old, right-handed; (2) No persistent or intermittent pain in the past three months; (3) No history of habitual smoking and drinking; (4) Non-professional athletes.

Exclusion criteria

Exclusion criteria: (1) A history of acute or persistent pain in the last three months; (2) Have a history of mental illness such as anxiety and depression, or cardiovascular disease such as hypertension and heart disease; (3) Present hand lesions or open wounds; (4) Long-term use of drugs that affect the nervous and musculoskeletal systems; (5) Participated in similar brain stimulation experiments in the past week; (6) Pregnant or lactating women; (7) Severe scalp trauma, extensive or open craniocerebral trauma, unable to place electrodes or may cause infection; (8) Subjects who have not obtained informed consent or are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Pressure pain threshold;

Secondary

MeasureTime frame
Cold pain threshold;Peak alpha frequency;conditioned pain modulation;

Countries

China

Contacts

Public ContactYuling Wang

The Sixth Affiliated Hospital of Sun Yat-sen University

wangyul@mail.sysu.edu.cn+86 130 5444 5587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026