Chronic pruritus
Conditions
Interventions
Moxibustion treatment group:Ignite 3-5 pieces of clear moxa stick about 4 cm in length, put it into the moxibustion apparatus, hold the moxibustion apparatus, and align the smoke outlet to the lesion
matching points: dryness and heat plus Chize, thenar
itching plus itching points.
Moxibustion combined with levocetirizine hydrochloride group:Levocetirizine dihydrochloride (Chongqing Huabang Pharmaceutical Effective Company, GYZZ: H20040249) was added to the moxibustion group, an
Nonmeridian nonacupoint control group:Choose the treatment of acupoints more than 0.5 inch peripheral distance outside the site, do not treat in the meridian passage position, the operation method and
Sponsors
The First Department of Oncology, The First Affiliated Hospital of Anhui University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: a. All cases were clinically or pathologically diagnosed as non-small cell lung cancer, the clinicopathological staging criteria were patients with stage II or lower, and genetic testing met the EGFR-TKI medication criteria; b. patients diagnosed with chronic pruritus; c.KPS (Karnofsk) score > 60 points, and the expected survival was more than 6 months; d. aged 18-70 years, primary school or above culture; e. stable condition, no severe heart, liver, brain, kidney and other organ damage or bone marrow hematopoietic dysfunction and bleeding risk; f. patients with clear consciousness, no dyslexia, can complete the questionnaire; g. patients agreed to participate in this clinical study, and signed the informed consent form.
Exclusion criteria
Exclusion criteria: a. clinical and imaging judgment of disease progression, patients who need to adjust the medication regimen; b. patients who need chemotherapy, targeted, immunotherapy during the study; c. patients who use other antipruritic drugs during the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified DUO Pruritus Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;DLQI score;Expression levels of serum TRPV1, PKC, SP, and PGE-2; | — |
Countries
China
Contacts
Public ContactZhu Yongfu
The First Affiliated Hospital of Anhui University of Chinese Medicine
Outcome results
None listed