malignant obstructive jaundice
Conditions
Interventions
OBT group:None
Non-OBT group:None
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1:No infection-related clinical symptoms and signs were found in the patient: body temperature monitoring was < 37.3C from admission to pre-operation, WBC count was 4~10×10^9/ L, neutrophil ratio was normal, mental consciousness was normal, and PCT was normal. 2:the patients had clinical manifestations of obstructive jaundice, such as yellow staining of skin and mucosa, yellow staining of sclera, skin itching, bradycardia, dark urine, lighter feces or white clay. 3:Serum total bilirubin increased, mainly direct bilirubin, alanine transaminase, aspartate aminotransferase, alkaline phosphatase and ?-glutamyltransferase increased or normal, urinary bilirubin increased, fecal bilirubin decreased or disappeared. 4:Imaging examination, including ultrasound, CT or MRCP, showing obstructive bile duct dilatation caused by malignant hepatobiliary and pancreatic diseases. 5:The competent surgeon assessed the need for surgery to relieve the obstruction.
Exclusion criteria
Exclusion criteria: 1:Age is <18 years old 2:Those who cannot tolerate surgery 3:Preoperative chemotherapy and / or radiotherapy, or immune drugs, or targeted drug therapy 4:There is a history of other abdominal operations within half a year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| white blood cell;neutrophilic granulocyte percentage;blood platelet count;procalcitonin;c reactive protein;interleukin-6;T lymphocyte subsets;immune globulin;complement in blood serum;Incidence of postoperative infectious complications (pneumonia, cholangitis, gastroenteritis, surgical site infection); | — |
Secondary
| Measure | Time frame |
|---|---|
| Clavien-Dindo complication rating;Incidence of postoperative sepsis;average stay;90-day postoperative mortality; | — |
Countries
China
Contacts
Public ContactZhang Wen
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed