Hypoproteinemia
Conditions
Interventions
Hypoproteinemia group: ALB<35g/L (Part 1):This part of the experiment is risk factor analysis, no intervention measures. Preoperative data of patients were collected for risk factor analysis.
Normal group ALB = 35g/L(Part 1):This part of the experiment is risk factor analysis, no intervention measures. Preoperative data of patients were collected for risk factor analysis.
General anesthesia group (Part 2):The patient received general anesthesia and a postoperative intravenous self-controlled analgesic pump (dispensing method: 1ug/kg.d sufentanil, the total amount is co
Compound epidural anesthesia group (Part 2):The patient received general anesthesia combined with epidural anesthesia. Before general anesthesia, epidural puncture and epidural catheter were placed. T
Sponsors
The First Affiliated Hospital of Nanjing Medical University in Huai'an
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Part 1: Patients who underwent radical surgery for malignant tumors in our hospital, aged = 18 years, regardless of gender or race, normal liver function before surgery, and no long-term history of taking drugs with obvious liver damage. All subjects signed informed consent forms. Part II: Patients who underwent radical surgery for malignant tumors in our hospital, aged = 18 years, regardless of gender or race, normal liver function before surgery, and no long-term history of taking drugs with obvious liver damage. All subjects signed informed consent.
Exclusion criteria
Exclusion criteria: Part 1: Age < 18 years old, emergency surgery, patients with acute or chronic hepatitis activity, pregnancy status, postoperative clear drug-induced liver injury, autoimmune diseases, preoperative abnormal liver function, contraindications to epidural anesthesia, those with abnormal preoperative risk factors related to hypoalbuminemia, and incomplete clinical data. Patients who explicitly refused to participate in the experiment. Part II: Age < 18 years old, emergency surgery, patients with acute or chronic hepatitis activity, pregnancy status, postoperative clear drug-induced liver injury, autoimmune diseases, preoperative abnormal liver function, contraindications to epidural anesthesia, those with abnormal preoperative risk factors related to hypoalbuminemia, and incomplete clinical data. Patients who explicitly refused to participate in the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactZhang Zhijie
The First Affiliated Hospital of Nanjing Medical University in Huai'an
Outcome results
None listed