Diseases treated by laparoscopic surgery
Conditions
Interventions
Dose decreasing group:The first patient took the dose of nalbuphine with positive reaction as the intervention measure, and then decreased by 0.01 mg / kg.
Sponsors
The People's Hospitai of Liupanshui
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ( 1 ) Laparoscopic surgery was planned to participate in this study and signed informed consent. ( 2 ) American Society of Anesthesiologists ( ASA ) grade ASA I-II ( 3 ) Age 18-65 years old, gender unlimited ( 4 ) Operation time = 2h ( 5 ) 18 kg / m2 = body mass index ( BMI ) = 30 kg / m2.
Exclusion criteria
Exclusion criteria: ( 1 ) Long-term use of sedative, analgesic and psychotropic drugs ( 2 ) History of alcohol or nalbuphine addiction ( 3 ) History of cardiovascular and cerebrovascular diseases ( 4 ) Narcotic drug allergy, family or personal history of suspected malignant hyperthermia ( 5 ) Severe liver and kidney dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified observer’s assessment of alert /sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay sedation score;VAS scores;numerical rating scale; | — |
Countries
China
Contacts
Public ContactWang Yong
The People's Hospitai of Liupanshui
Outcome results
None listed