Leptomeningeal metastasis of NSCLC
Conditions
Interventions
Gold Standard:The diagnosis of LM is confirmed in the presence of tumour cells in the CSF or by a positive leptomeningeal biopsy (type I). In the absence of tumour cells in the CSF or histological con
Index test:Tumor markers detection in cerebrospinal fluid
Sponsors
The First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Patients with leptomeningeal metastasis of NSCLC. 2.Control group: NSCLC patients with brain parenchymal metastasis without leptomeningeal metastasis. 3.Control group: patients with primary central nervous system tumors and non-tumor diseases.
Exclusion criteria
Exclusion criteria: 1.Patients with small cell lung cancer, other solid tumors, and hematological tumors. 2.NSCLC patients with brain parenchymal metastases undergoing surgical treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Receiver operating characteristic,ROC;sensibility;specificity;accuracy;AUC(Area Under Curve); | — |
Countries
China
Contacts
Public ContactQingsheng Xu
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed