Repeated transplantation failure under IVF with anxiety
Conditions
Interventions
experimental group:The treatment group was treated with auricular acupuncture and western medicine.
Sham acupuncture group:The patients in the sham-acupuncture group received placebo acupuncture plus western medication.
Control group:The patients in the control group were treated with GnRHa down-regulating hormone regimen and only western medicine.
Sponsors
Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: ? patients with two or more times of IVF-ET and no pregnancy or more than 3 high-quality embryos transferred without pregnancy, and planned to undergo frozen-thawed embryo transfer (FET); ? Patients and their spouses aged from 25 to 40 years old; ? no serious psychological trauma in the past year; ? there are still more than 2 high-quality frozen embryos; ? Hamilton Anxiety Scale (HAM-A) > 7; ? those who signed the informed consent form after understanding the study process. ? Women with basic ability to read, communicate and complete questionnaires independently.
Exclusion criteria
Exclusion criteria: ? Endometrial lesions, such as endometrial polyps, intrauterine adhesions, submucosal myoma, thin endometrium (thickness < 7mm), endometriosis, etc.; ? uterine malformation and adenomyosis; ? women with a history of recurrent miscarriage (defined as =2 clinical pregnancy failures) ? accompanied by severe hypertension, liver and kidney function damage, mental illness unable to cooperate with treatment or HAM-A score =24; ? repeated transplantation failure caused by other clear reasons, such as chromosomal abnormalities; ? patients who had received psychological intervention such as psychological counseling before this study; ? Patients with poor compliance, refusing to participate in the study or sign the informed consent, and difficult to follow up; ? Participating in other clinical investigators. ? receiving acupuncture, traditional Chinese medicine, or physical therapy within 3 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAM-A; | — |
Secondary
| Measure | Time frame |
|---|---|
| SAS;rate of pregnancy;NE;serotonin; | — |
Countries
China
Contacts
Public ContactLai Xin
The sixth affiliated hospital of Sun yat-sen University
Outcome results
None listed