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The application of manual jet ventilation and rapid exchange ventilation through nasal humidification in children undergoing rigid and endoscopic airway exploration surgery

The application of manual jet ventilation and rapid exchange ventilation through nasal humidification in children undergoing rigid and endoscopic airway exploration surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078512
Enrollment
Unknown
Registered
2023-12-11
Start date
2023-12-11
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children with airway foreign bodies, new organisms in the airway, airway stenosis, pneumonia, etc.

Interventions

Group MJV:Using MJV for ventilation management during surgery
Group MJV+THRIVE:Using MJV and THRIVE for ventilation management during surgery

Sponsors

Eye & ENT Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1: Children aged 2 years or older to 12 years or younger 2: ASA physical status I or III 3.Children undergoing removal of airway foreign bodies/alveolar lavage/removal of new airway organisms/dilation of airway stenosis under general anesthesia

Exclusion criteria

Exclusion criteria: 1. Known or expected difficulty in intubation 2. Known or expected difficulty in mask ventilation 3. Oxygen dependence 4. Having congenital heart disease or respiratory developmental abnormalities 5. Contraindications to the use of neuromuscular blockade 6. Risk of reflux and aspiration 7. Individuals with a history of allergies to drugs used in anesthesia and surgery 8. Recent skull base/maxillofacial fractures 9. Patients with nasal congestion who cannot receive nasal ventilation (epistaxis/deviation of nasal septum, etc.)

Design outcomes

Primary

MeasureTime frame
Average number of presses per minute for manual jet ventilation;Incidence of respiratory adverse events (RAEs) after airway establishment;

Secondary

MeasureTime frame
Mean blood oxygen saturation of children during surgery;The number of times surgeons interrupt operations during surgery;The highest value of intraoperative percutaneous CO2;Replacing ventilation tools during surgery;Pulmonary complications during surgery;

Countries

China

Contacts

Public ContactYirong Cai

Eye & ENT Hospital, Fudan University

381935641@qq.com+86 136 7199 2351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026