The role and predictive value of renin-angiotensin-aldosterone system in acute renal injury after laparoscopic radical nephrectomy

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300078503

Enrollment

Unknown

Registered

2023-12-11

Start date

2023-12-11

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury

Interventions

Trail group:No

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing RN under general anesthesia in our hospital. 2.The age is between 40 and 80. 3.ASA grade ?-?. 4. The heart, liver and kidney function were normal before operation. 5. Informed consent was obtained from all individual participants included in the study.

Exclusion criteria

Exclusion criteria: 1 .Patients with solitary kidney. 2.Nephrotoxic drugs were used before operation. 3.History of secondary renal operation. 4.There was a history of rescue before operation. 5.Major complications occurred during and after operation.

Design outcomes

Primary

Measure	Time frame
renin ;Ang?;AGT;Ang1-7;aldosterone;Serum creatinine;	—

Secondary

Measure	Time frame
Glomerular filtration rate;serum cystatin;	—

Countries

China

Contacts

Public ContactYongzhe Liu

The Third Medical Center of Chinese PLA General Hospital

lyzgao@qq.com+86 158 1133 1366

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026