portal vein thrombosis/cavernous transformation of portal vein
Conditions
Interventions
TEPS group:TEPS operation
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 to 75 years; 2. Diagnosed PVT/CTPV, confirmed EGVB based on endoscopy examination; 3. Child-Pugh score is less than10; 4. Completely or partially unobstructed SMV according to imaging examination; 5. Understand the risk associated with surgery and endoscopic treatment, and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Complicated with non-variceal gastrointestinal bleeding (acute erosive gastritis, peptic ulcer, gastric cancer); 2. Previous endoscopic treatment for EGVB within the past year; 3. Previous TIPS, surgical disconnection, or other abdominal surgeries; 4. Complicated with spontaneous peritonitis that cannot be controlled by combined medical treatment; 5. Uncontrolled EGVB or stabilized for less than one week; 6. Child-Pugh score is greater than or equal to 10; 7. Complicated with infection and shock before operation that cannot tolerate invasive procedures and treatment; 8. Dysfunction of organs including heart, lung, kidney and brain, and pulmonary hypertension; 9. Liver cancer and other malignant tumors beyond Milan criteria; 10. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Uncontrolled rupture or rebleeding of esophageal and gastric varices after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Risk associated with surgery or endoscopic treatment;Complications associated with portal hypertension;Other adverse events;Disease burden; | — |
Countries
China
Contacts
Public ContactHao Wu
Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University
Outcome results
None listed